Dallas -based biotechnology company Colossal BioscienCes almost opened a breakthrough in the world of science. The company has announced that it has successfully returned the “Ulukurt” (Aenocyon Dirus) species, which was exhausted about 12,500 years ago. According to the statement, three healthy puppies (Romulus, Remus and Khaleesi) were born using ancient DNA, cloning and gene editing technologies. For the first time in the world, this development went down in history as the “re -revitalization of a species; At least the company says that.

Ulukurtlar returned

This species inspired the legendary wolves in the Game of Thrones series was one of the most feared predators of North America in the prehistoric period. The larger structures than gray wolves, thick furs and strong jaws, this creature was re -returned to life. Colossal’s founding partner and CEO Ben Lamm said that their technologies work, while one of the 13,000 -year -old teeth and the other from a 72,000 -year -old skull, said they obtained healthy offspring.

In October last year, the newborn Ulukurt puppies (Romulus and Remus, his sisters Khaleesi was born 3 months later), the location kept secret and established on an area of ​​2,000 acres, surrounded by a 3 -meter -high “zoo standards” facility surrounded by fences. Alan, security guards, drones and live broadcast cameras are watched 24/7. The facility was approved by the American Humanitarian Association and is reportedly registered to the US Department of Agriculture.

Scientists created high -quality genome maps of this species using ancient DNAs obtained from two different Ulukurt fossils. Genomas, gray wolves, jackal and fox compared with living species by comparing the species – for example white hairs, thick fur and head structure – were determined.

Thanks to CRISPR technology, a total of 20 arrangements were made on 14 different genes in gray wolf cells. Genetically arranged cells were transferred to dog eggs and placed in carrier mothers. Two male and one female puppies were born as a result of three successful pregnancy. The carrier mothers were domestic dogs selected from large breeds. The emerging creatures carry gray wolf genes to a large extent.

Colossal Biosciences has been aiming to bring back species such as Mamut, Dodo and Tasmanian tiger since it was founded in 2021 by the famous geneticist George Church of Harvard University. The company has collected over $ 435 million to date. The Mamut project, which we transferred the details of the last month, is expected to result in the first offspring in 2028.

Can save endangered species

Colossal emphasizes that the gene regulation and cloning technologies developed in Ulukurt project can play a revolutionary role not only in the return of extinct species, but also in the protection of animals under the danger of extinction. In this context, the company announced that it has managed to produce two groups of offspring for the world’s most threatened wolf types (Canis Rufus).

Newborn Red Wolves were born with a less invasive and animal -friendly cloning technique developed during Ulukurt research. This method ensures that the carrier animals are less risky and increases the embryo holding rates. Colossal’s goal is to implement these technologies in other species under endangered extinction in the future.

There are also discussions

For some, these are the “Frankenstein experiments of the modern age, but the technologies behind it are admirable. However, there is no discussions. Even though the offspring of the Ulukurts are produced, it is difficult to say whether they are “the same ile as the original species. Newscientist reports that these wolves are actually genetically modified gray wolves that resemble Ulukurt based on limited gene regulations.

In addition, it is unclear whether these creatures will live in a real ecosystem. Although the company’s long -term plan is integrated into natural environments, such as genetically reconstructed mammoths and ulukurtlar, this scenario seems quite far. According to experts, it is unclear what these new animals will really do. It is a fact that it is not possible for the mammoths that the company works in today’s world. Because the climate has changed and most of the living spaces disappeared.