There are many scientific studies on the benefits of coffee, which is a part of most people’s daily lives, but there is no clarity on how it provides these benefits. A new study on coffee reveals the reason behind caffeine’s ability to prevent cardiovascular disease.
Caffeine makes it easier for the liver to break down LDP cholesterol
Two to three cups of coffee a day contain enough caffeine to trigger a cascading effect that reduces low-density lipoprotein (LDL) or “bad” cholesterol levels, McMaster University researchers say .
The team found that regular caffeine consumption was associated with a decrease in a protein called PCSK9 in the bloodstream. People with high LDL cholesterol levels are more likely to have cardiovascular diseases such as heart attack, stroke and heart failure. The decrease in PCSK9 level that occurs with coffee consumption increases the liver’s ability to break down LDL cholesterol.
Caffeine, which shows its effects directly on PCSK9, also has the ability to inhibit the activation of a protein called SREBP2, which is stated to be associated with a number of cardiometabolic diseases. Reducing the activation of the SREBP2 protein reduces the level of PCSK9 in the blood.
The researchers also found that caffeine and its derivatives were beyond what was observed in the study. They’re also exploring additional health benefits. They’ve also created new caffeine derivatives that lower blood PCSK9 levels and hope to make them a new type of treatment for lowering cholesterol.
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