You may have read hundreds of news articles under the heading ‘The cure for cancer has been found’. However, cancer is still one of the biggest threats today, and unfortunately, researchers continue to work on this issue, since there is still no definitive cure yet. One of the closest we got to finding a cure was the discovery made by Aziz Sancar the other day.
Although Sancar’s discovery covers the type of cancer that occurs in the brain, the research we will give today aims to eliminate many types of cancer. In the study led by researchers at the University of Texas, a molecule was developed that treats even the most difficult types of cancer. This new molecule, the details of which we will talk about below, has the ability to treat difficult types of cancer, including breast cancer.
New molecule finds cancer cells weak spot
This new molecule, called ERX-41, does something that previous cancer drugs could not do. Researchers who discovered that ERX-41 binds to a cellular protein called lysosomal acid lipase A (LIPA) realized that they could use this feature of the molecule for therapeutic purposes.
Unlike previous drugs, ERX-41 can find a weak point of cancer cells and destroy them. Researchers tested a new compound he synthesized, called ERX-41, for its effects against breast cancer cells, both with and without estrogen receptors, and got positive results. Let’s read the working principle of ERX-41 from the mouth of the researchers:
“A tumor cell needs to produce a lot of protein to grow rapidly, and this puts stress on the endoplasmic reticulum. Cancer cells produce significantly more LIPA than healthy cells. ERX-41 binds to LIPA, jamming protein processing in the endoplasmic reticulum. , which in turn swells and leads to cell death.”
It was also discovered that ERX-41 is effective against other types of cancer with high endoplasmic reticulum stress, including difficult-to-treat pancreatic and ovarian cancers and glioblastoma, the most aggressive and deadly primary brain cancer. If you want more details, you can take a look at the source of the research.
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