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Artificial Mouse Embryo Grown Outside the Womb for the First Time

Scientists have grown a completely artificial stem cell-derived embryo without the need for a uterus, eggs and sperm. The new discovery is thought to be essential for artificial organs.
 Artificial Mouse Embryo Grown Outside the Womb for the First Time
READING NOW Artificial Mouse Embryo Grown Outside the Womb for the First Time

While the demand of humanity for organ transplantation is increasing day by day, this demand is very difficult to meet today. While the scarcity of organ donors and the difficulties in ensuring the preservation of organs are the main reasons for this situation, the scientific world is working on alternative ways such as artificial organs and pig organs.

Today, a new milestone came from the world of science. According to the study published in the journal Cell, for the first time in history, scientists managed to grow artificial mouse embryos without the need for any uterus, sperm or eggs. The new discovery is thought to be the first step in creating organs from scratch.

Many of the embryos died, but the survivors continued to thrive:

  • The day-to-day development process of embryos

Sharing that they see the embryo as the best ‘organ making machine’ and ‘three-dimensional biological printer’, scientists derived artificial embryos from stem cells. The chemical signals normally sent to these cells by the body to tell them ‘what to do’ have been artificially imitated by the scientists.

Many of the synthetic embryos died during this stage. However, it was observed that some of the embryos continued to develop for about 8.5 days. Moreover, this time was twice as long as the normal time spent in the pregnancy of the mice. Embryos developing at this stage had 95% similarity to normal mouse embryos and had completed placental development up to the development of the spine, digestive tract, a beating heart, and brain.

In the new development, which makes us think that there will be no need for organ donor in the future, the scientists shared that the next step will be to understand how the stem cells understand what they should do and how they determine the position they should be in the embryo.

In addition, it was stated that ethical discussions on artificial human embryos should be brought to the agenda again, and that the best legal and ethical framework should be established for this.

So, what do you think about this subject?

Previously, a non-artificial embryo directly from mice was grown outside the womb:

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