Scientists researching a new cancer treatment method state that they have developed an ‘invisibility cloak’ for therapeutic bacteria. This cloaking system will allow for more effective drug delivery to tumors.
It can solve the problems of traditional methods
Traditional cancer treatment methods use therapeutic bacteria, but this brings some difficulties. The rapid growth of bacteria in the body can cause the body’s immune system to view them as a threat.
For their new method, the researchers focused on capsular polysaccharides (CAPs), which help many bacteria protect themselves from attack, including their immune systems. The new system, which they call iCAP, will allow control of how long bacteria can survive in human blood.
iCAP will also hide therapeutic bacteria up to the area where the cancer virus is located, thus increasing the maximum tolerable bacterial dose.
Moderna started Phase 1 trials of 3 different mRNA HIV vaccines
The researchers observed that with the new system, they could increase the maximum tolerable bacterial dose 10-fold using mouse tumor models. The results are expected to have an even greater impact on human patients than mice.
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